Architectural and functional diversity of polycomb group response elements in Drosophila.

doi:10.1534/genetics.113.153247

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Article

Architectural and functional diversity of polycomb group response elements in Drosophila.

Genetics - 1 Oct 2013

Brown J Lesley, Kassis Judith A

Abstract excerpt

Polycomb group response elements (PREs) play an essential role in gene regulation by the Polycomb group (PcG) repressor proteins in Drosophila. PREs are required for the recruitment and maintenance of repression by the PcG proteins. PREs are made up of binding sites for multiple DNA-binding proteins, but it is still unclear what combination(s) of binding sites is required for PRE activity. Here we compare the...

Topics

Animals
Binding Sites
Chromatin
DNA-Binding Proteins
Drosophila Proteins
Drosophila melanogaster
Gene Expression Regulation, Developmental
Gene Silencing
Genetic Variation
Polycomb-Group Proteins
Regulatory Sequences, Nucleic Acid
Response Elements

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Identifiers

PMID: 23934890
DOI: 10.1534/genetics.113.153247
PMCID: PMC3781969

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