Article
A Polycomb and GAGA dependent silencer adjoins the Fab-7 boundary in the Drosophila bithorax complex.
Genetics - 1 Aug 1997
Hagstrom K, Muller M, Schedl P
Abstract excerpt
The homeotic genes of the Drosophila bithorax complex are controlled by a large cis-regulatory region that ensures their segmentally restricted pattern of expression. A deletion that removes the Frontabdominal-7 cis-regulatory region (Fab-7') dominantly transforms parasegment 11 into parasegment...
Topics
- Alleles
- Animals
- Chromatin
- Crosses, Genetic
- DNA
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Eye Color
- Female
- Gene Deletion
- Gene Expression Regulation, Developmental
- Genes, Homeobox
- Genes, Insect
- Genetic Complementation Test
- Heterozygote
- Homeodomain Proteins
- Homozygote