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Models for predicting BRCA1 and BRCA2 mutations in Han Chinese familial breast and/or ovarian cancer patients.

Breast cancer research and treatment - 1 Feb 2009

Rao Nan-Yan, Hu Zhen, Li Wen-Feng, Huang Juan, Ma Zhong-Liang, Zhang Bin, Su Feng-Xi, Zhou Jie, Di Gen-Hong, Shen Kun-Wei, Wu Jiong, Lu Jin-Song, Luo Jian-Min, Yuan Wen-Tao, Shen Zhen-Zhou, Huang Wei, Shao Zhi-Ming

Abstract excerpt

PURPOSE: Our aim was to find an appropriate method to estimate the likelihood that a family history of cancer was a result of a mutation in the BRCA1 or BRCA2 genes. We also compared the performance of the established method with three different methods (Couch, Sh-E and BRCApro) to identify an alternative strategy for genetic council targeted to the specified population. PATIENTS AND METHODS: The family history...

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Source

Identifiers

PMID: 18343994
DOI: 10.1007/s10549-008-9965-9

Genes

BRCA2
BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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