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BRCA1 and BRCA2 mutation predictions using the BRCAPRO and Myriad models in Korean ovarian cancer patients.

Gynecologic oncology - 1 Apr 2017

Eoh Kyung Jin, Park Ji Soo, Park Hyung Seok, Lee Seung-Tae, Han Jeongwoo, Lee Jung-Yun, Kim Sang Wun, Kim Sunghoon, Kim Young Tae, Nam Eun Ji

Abstract excerpt

OBJECTIVE: To evaluate the predictive efficacies including sensitivity and positive predictive value of the genetic risk prediction model BRCAPRO and the Myriad BRCA risk calculator in Korean ovarian cancer patients. METHODS: Individuals undergoing genetic testing for BRCA mutations from November 2010-August 2016 were recruited from the Department of Obstetrics and Gynecology at a single institute in Korea. The...

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Identifiers

PMID: 28159408
DOI: 10.1016/j.ygyno.2017.01.026

Genes

BRCA1
BRCA2

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