Article
KOHBRA BRCA risk calculator (KOHCal): a model for predicting BRCA1 and BRCA2 mutations in Korean breast cancer patients.
Journal of human genetics - 1 May 2016
Kang Eunyoung, Park Sue K, Lee Jong Won, Kim Zisun, Noh Woo-Chul, Jung Yongsik, Yang Jung-Hyun, Jung Sung Hoo, Kim Sung-Won
Abstract excerpt
The widely used Western BRCA mutation prediction models underestimated the risk of having a BRCA mutation in Korean breast cancer patients. This study aimed to identify predictive factors for BRCA1/2 mutations and to develop a Korean BRCA risk calculator. The model was constructed by logistic regression model, and it was based on the Korean Hereditary Breast Cancer study, in which 1669 female patients were...
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