Article

Development of a novel prediction model for carriage of BRCA1/2 pathogenic variant in Japanese patients with breast cancer based on Japanese Organization of Hereditary Breast and Ovarian Cancer registry data

2024-06-11

Abstract excerpt

<title>Abstract</title> <bold>Purpose:</bold> With the increasing demand for <italic>BRCA</italic> genetic testing, most existing prediction models were developed using data from individuals of European descent. This study aimed to identify clinicopathological factors of hereditary breast and ovarian cancer (HBOC) syndrome and develop the first Japanese-specific prediction model for <italic>BRCA</italic> patho...

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Literature Corpus work: c00076b4-3c2a-577a-884f-da8b175a9bd2
DOI: 10.21203/rs.3.rs-4478776/v1

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