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Article

Evaluating the performance of models for predicting the BRCA germline mutations in Han Chinese familial breast cancer patients.

Breast cancer research and treatment - 1 Aug 2009

Rao Nan-Yan, Hu Zhen, Yu Jin-Ming, Li Wen-Feng, Zhang Bin, Su Feng-Xi, Wu Jiong, Shen Zhen-Zhou, Huang Wei, Shao Zhi-Ming

Abstract excerpt

PURPOSE: Established models (Penn, Myraid and BRCApro) are useful of estimating the probability that a person has a BRCA mutation. But the value of these models in Chinese population is unclear. The aim of the study is to evaluate the performance of three models on the assisting in pre-test genetic risk counseling. METHODS: Three risk assessment models, Penn II, Myriad and BRCApro, were applied to 212 familial...

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Source

Identifiers

PMID: 18807178
DOI: 10.1007/s10549-008-0181-4

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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