Article
Polymorphisms in the PTPN22 region are associated with psoriasis of early onset.
The British journal of dermatology - 1 May 2008
Smith Rh Ll, Warren R B, Eyre S, Ke X, Young H S, Allen M, Strachan D, McArdle W, Gittins M P, Barker J N W N, Griffiths C E M, Worthington J
Abstract excerpt
BACKGROUND: Psoriasis, a chronic inflammatory skin disease, affects approximately 2% of the population worldwide. Although the aetiology of psoriasis is poorly understood, patients with disease of early onset (Type I, age of onset<or=40 years) usually have a strong genetic component to the disease. OBJECTIVES: The purpose of this study was to investigate the role of the protein tyrosine phosphatase nonreceptor...
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