Article
Evidence for susceptibility determinant(s) to psoriasis vulgaris in or near PTPN22 in German patients.
Journal of medical genetics - 1 Jun 2006
Hüffmeier U, Steffens M, Burkhardt H, Lascorz J, Schürmeier-Horst F, Ständer M, Kelsch R, Baumann C, Küster W, Mössner R, Reich K, Wienker T F, Traupe H, Reis A
Abstract excerpt
INTRODUCTION: Variant R620W of protein tyrosine phosphatase non-receptor type 22 (PTPN22) has consistently been reported as a susceptibility factor for several autoimmune diseases. We investigated its role in susceptibility to psoriasis, the relevance of possibly other disease-causing variants, and interdependency of the major risk factor for psoriasis at PSORS1. METHODS: R620W was tested in a case-control study...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.