Article
Genetic polymorphisms associated with psoriasis and development of psoriatic arthritis in patients with psoriasis.
PloS one - 1 Jan 2018
Loft Nikolai Dyrberg, Skov Lone, Rasmussen Mads Kirchheiner, Gniadecki Robert, Dam Tomas Norman, Brandslund Ivan, Hoffmann Hans Jürgen, Andersen Malene Rohr, Dessau Ram Benny, Bergmann Ann Christina, Andersen Niels Møller, Abildtoft Mikkel Kramme, Andersen Paal Skytt, Hetland Merete Lund, Glintborg Bente, Bank Steffen, Vogel Ulla, Andersen Vibeke
Abstract excerpt
BACKGROUND: Psoriasis (PsO) is a chronic inflammatory disease with predominantly cutaneous manifestations. Approximately one third of patients with PsO develop psoriatic arthritis (PsA), whereas the remaining proportion of patients has isolated cutaneous psoriasis (PsC). These two phenotypes share common immunology, but with different heredity that might in part be explained by genetic variables. METHODS: Using a...
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