Article
Polymorphisms Associated with Age at Onset in Patients with Moderate-to-Severe Plaque Psoriasis.
Journal of immunology research - 1 Jan 2015
Prieto-Pérez Rocío, Solano-López Guillermo, Cabaleiro Teresa, Román Manuel, Ochoa Dolores, Talegón María, Baniandrés Ofelia, López-Estebaranz José Luis, de la Cueva Pablo, Daudén Esteban, Abad-Santos Francisco
Abstract excerpt
Psoriasis is a chronic skin disease in which genetics play a major role. Although many genome-wide association studies have been performed in psoriasis, knowledge of the age at onset remains limited. Therefore, we analyzed 173 single-nucleotide polymorphisms in genes associated with psoriasis and other autoimmune diseases in patients with moderate-to-severe plaque psoriasis type I (early-onset, <40 years) or type...
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