Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PTPN22 C1858T and the risk of psoriasis: a meta-analysis.

Molecular biology reports - 1 Aug 2012

Chen Yu-Fu, Chang Jeffrey S

Abstract excerpt

Psoriasis is a chronic autoimmune skin disease with both environmental and genetic risk factors. Previous studies of the association between psoriasis and PTPN22 C1858T (rs2476601), a gain of function variant associated with a stronger inhibitory effect of T-lymphocytes, have produced inconsistent results. The purpose of the current study is to evaluate the association between PTPN22 C1858T and psoriasis using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Arthritis, Psoriatic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to PTPN22 gene

Share to Genetic Predisposition to Disease

Share to Odds Ratio

Share to Polymorphism, Single Nucleotide

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Share to Psoriasis

Source

Identifiers

PMID: 22544573
DOI: 10.1007/s11033-012-1630-z

Genes

PTPN22

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PTPN22 C1858T and the risk of psoriasis: a meta-analysis.PMID 22544573Read ↗

The PTPN22 C1858T functional polymorphism and autoimmune diseases--a meta-analysis.Semantic proximity Read ↗

Polymorphisms in the PTPN22 region are associated with psoriasis of early onset.Semantic proximity Read ↗

Meta-analysis reveals an association of PTPN22 C1858T with autoimmune diseases, which depends on the localization of the affected tissue.Semantic proximity Read ↗

Genetic Polymorphism of PTPN22 in Autoimmune Diseases: A Comprehensive Review.Semantic proximity Read ↗

Deciphering autoimmune susceptibility: a meta-analysis of PTPN22 gene variants.Semantic proximity Read ↗

The non-synonymous C1858T substitution in the PTPN22 gene is associated with susceptibility to the severe forms of alopecia areata.Semantic proximity Read ↗

PTPN22 1858C > T polymorphism and susceptibility to systemic lupus erythematosus: a meta-analysis update.Semantic proximity Read ↗

Association between the PTPN22 +1858 C/T polymorphism and psoriatic arthritis.Semantic proximity Read ↗

Identification of a missense variant in LNPEP that confers psoriasis risk.Semantic proximity Read ↗

Evidence for susceptibility determinant(s) to psoriasis vulgaris in or near PTPN22 in German patients.Semantic proximity Read ↗

The association between the PTPN22 C1858T polymorphism and systemic lupus erythematosus: a meta-analysis update.Semantic proximity Read ↗

Association of rs610604 in TNFAIP3 and rs17728338 in TNIP1 gene polymorphisms with psoriasis susceptibility: A meta-analysis of case-control studiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.