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A distinct ERCC1 haplotype is associated with mRNA expression levels in prostate cancer patients

11 Mar 2008

Abstract excerpt

Both genetic variants and messenger RNA (mRNA) expression of DNA repair and tumor suppressor genes have been investigated as molecular markers for therapy outcome. However, the phenotypic impact of genetic variants often remained unclear, thus the rationale of their use in risk prediction may be limited. We therefore analyzed genetic variants together with anthropometric and lifestyle factors to see how these...

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PMID: 18332046
DOI: 10.1093/carcin/bgn067

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