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Article

Single nucleotide polymorphisms of the DNA repair gene XPD/ERCC2 alter mRNA expression.

Pharmacogenetics and genomics - 1 Nov 2007

Wolfe Kevin J, Wickliffe Jeffrey K, Hill Courtney E, Paolini Moreno, Ammenheuser Marinel M, Abdel-Rahman Sherif Z

Abstract excerpt

OBJECTIVES: Epidemiological studies documented associations between single nucleotide polymorphisms (SNPs) in the nucleotide excision repair gene XPD/ERCC2 and cancer risk. Little is known, however, about the underlying mechanisms for these associations. We explored a novel mechanism that could f...

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Source

Identifiers

PMID: 18075460
DOI: 10.1097/FPC.0b013e3280115e63

Genes

ERCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18075460-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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