Article
Inter-individual variation in nucleotide excision repair in young adults: effects of age, adiposity, micronutrient supplementation and genotype.
The British journal of nutrition - 1 May 2009
Tyson John, Caple Fiona, Spiers Alison, Burtle Brian, Daly Ann K, Williams Elizabeth A, Hesketh John E, Mathers John C
Abstract excerpt
Nucleotide excision repair (NER) is responsible for repairing bulky helix-distorting DNA lesions and is essential for the maintenance of genomic integrity. Severe hereditary impairment of NER leads to cancers such as those in xeroderma pigmentosum, and more moderate reductions in NER capacity hav...
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