Article
A prospective study of XRCC1 haplotypes and their interaction with plasma carotenoids on breast cancer risk.
Cancer research - 1 Dec 2003
Han Jiali, Hankinson Susan E, De Vivo Immaculata, Spiegelman Donna, Tamimi Rulla M, Mohrenweiser Harvey W, Colditz Graham A, Hunter David J
Abstract excerpt
The XRCC1 protein is involved in the base excision repair pathway through interactions with other proteins. Polymorphisms in the XRCC1 gene may lead to variation in repair proficiency and confer inherited predisposition to cancer. We prospectively assessed the associations between polymorphisms and haplotypes in XRCC1 and breast cancer risk in a nested case-control study within the Nurses' Health Study (incident...
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