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Frequency distribution of DNA repair genes ERCC1 and ERCC2 polymorphisms in South Indian healthy population.

Environmental toxicology and pharmacology - 1 Sept 2014

Rao Katiboina Srinivasa, SureshKumar Srinivasamurthy, Umamaheswaran Gurusamy, Paul Abialbon, Dubashi Biswajit, Gunaseelan Karunanithi, Dkhar Steven Aibor

Abstract excerpt

DNA repair genes are crucial in maintaining the integrity of the whole genome. Single nucleotide polymorphisms (SNPs) in DNA repair genes have been attributed to the development of various cancers. SNPs of DNA repair genes (ERCC1 and ERCC2) have been implicated in the causation of various cancers as well as inter-individual variability in the therapeutic outcomes of platinum based therapy. Thus establishing the...

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PMID: 25155628
DOI: 10.1016/j.etap.2014.07.022

Genes

ERCC1
ERCC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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