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Article

Genetic variation predicting cisplatin cytotoxicity associated with overall survival in lung cancer patients receiving platinum-based chemotherapy.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 2011

Tan Xiang-Lin, Moyer Ann M, Fridley Brooke L, Schaid Daniel J, Niu Nifang, Batzler Anthony J, Jenkins Gregory D, Abo Ryan P, Li Liang, Cunningham Julie M, Sun Zhifu, Yang Ping, Wang Liewei

Abstract excerpt

PURPOSE: Inherited variability in the prognosis of lung cancer patients treated with platinum-based chemotherapy has been widely investigated. However, the overall contribution of genetic variation to platinum response is not well established. To identify novel candidate single nucleotide polymorphisms (SNP)/genes, we carried out a genome-wide association study (GWAS) for cisplatin cytotoxicity by using...

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Identifiers

PMID: 21775533
DOI: 10.1158/1078-0432.CCR-11-1133
PMCID: PMC3167019

Genes

DAPK3
METTL6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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