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Article

Use of cell lines in the investigation of pharmacogenetic loci.

Current pharmaceutical design - 1 Jan 2009

Zhang Wei, Dolan M Eileen

Abstract excerpt

Drug response and toxicity, complex traits that are often highly varied among individuals, likely involve multiple genetic and non-genetic factors. Pharmacogenomic research aims to individualize therapy in an effort to maximize efficacy and minimize toxicity for each patient. Cell lines can be used as a model system for cellular pharmacologic effects, which include, but are not limited to, drug-induced...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19925429
DOI: 10.2174/138161209789649475
PMCID: PMC2782819

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