Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mapping genes that contribute to daunorubicin-induced cytotoxicity.

Cancer research - 1 Jun 2007

Duan Shiwei, Bleibel Wasim K, Huang Rong Stephanie, Shukla Sunita J, Wu Xiaolin, Badner Judith A, Dolan M Eileen

Abstract excerpt

Daunorubicin is an anthracycline antibiotic agent used in the treatment of hematopoietic malignancies. Toxicities associated with this agent include myelosuppression and cardiotoxicity; however, the genes or genetic determinants that contribute to these toxicities are unknown. We present an unbiased genome-wide approach that incorporates heritability, whole-genome linkage analysis, and linkage-directed...

Topics

Join the communities discussing this publication.

Antibiotics, Antineoplastic
Cell Line, Tumor
Chromosome Mapping
Daunorubicin
Genetic Linkage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 17545624
DOI: 10.1158/0008-5472.CAN-06-4431
PMCID: PMC2735868

Genes

GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mapping genes that contribute to daunorubicin-induced cytotoxicity.PMID 17545624Read ↗

Genetic variants contributing to daunorubicin-induced cytotoxicity.Semantic proximity Read ↗

Genome-wide discovery of loci influencing chemotherapy cytotoxicitySemantic proximity Read ↗

Susceptibility loci involved in cisplatin-induced cytotoxicity and apoptosis.Semantic proximity Read ↗

A genome-wide approach to identify genetic variants that contribute to etoposide-induced cytotoxicity.Semantic proximity Read ↗

Genetic and epigenetic variants contributing to clofarabine cytotoxicity.Semantic proximity Read ↗

Pharmacogenomic Characterization of US FDA-approved Cytotoxic DrugsSemantic proximity Read ↗

Identifying genetic variants that contribute to chemotherapy-induced cytotoxicity.Semantic proximity Read ↗

Impact of the 1000 genomes project on the next wave of pharmacogenomic discovery.Semantic proximity Read ↗

Identification of genomic regions contributing to etoposide-induced cytotoxicity.Semantic proximity Read ↗

Genetic variants associated with carboplatin-induced cytotoxicity in cell lines derived from Africans.Semantic proximity Read ↗

Heritable and non-genetic factors as variables of pharmacologic phenotypes in lymphoblastoid cell lines.Semantic proximity Read ↗

Genome-wide local ancestry approach identifies genes and variants associated with chemotherapeutic susceptibility in African Americans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.