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Article

Application of next generation sequencing to CEPH cell lines to discover variants associated with FDA approved chemotherapeutics.

BMC research notes - 12 Jun 2014

Hariani Gunjan D, Lam Ernest T, Lam Ernest J, Havener Tammy, Kwok Pui-Yan, McLeod Howard L, Wagner Michael J, Motsinger-Reif Alison A

Abstract excerpt

BACKGROUND: The goal of this study was to perform candidate gene association with cytotoxicity of chemotherapeutics in cell line models through resequencing and discovery of rare and low frequency variants along with common variations. Here, an association study of cytotoxicity response to 30 FDA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24924344
DOI: 10.1186/1756-0500-7-360
PMCID: PMC4068968

Genes

NQO1
ABCC5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24924344-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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