Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chemotherapeutic-induced apoptosis: a phenotype for pharmacogenomics studies.

Pharmacogenetics and genomics - 1 Aug 2011

Wen Yujia, Gorsic Lidija K, Wheeler Heather E, Ziliak Dana M, Huang Rong Stephanie, Dolan Mary Eileen

Abstract excerpt

AIM: To determine whether cellular apoptosis is a suitable phenotypic trait for pharmacogenomics studies by evaluating caspase 3/7-mediated activity in lymphoblastoid cell lines after treatment with six chemotherapeutic agents: 5'-deoxyfluorouridine, pemetrexed, cytarabine, paclitaxel, carboplatin, and cisplatin. MATERIALS AND METHODS: Using monozygotic twin pair and sibling pair lymphoblastoid cell lines, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Pharmacological
Share to Carboplatin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caspases

Share to Cisplatin

Share to Cytarabine

Share to Glutamates

Share to Paclitaxel

Share to Pemetrexed

Source

Open in PubMed Open full text

Identifiers

PMID: 21642893
DOI: 10.1097/FPC.0b013e3283481967
PMCID: PMC3134538

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chemotherapeutic-induced apoptosis: a phenotype for pharmacogenomics studies.PMID 21642893Read ↗

Susceptibility loci involved in cisplatin-induced cytotoxicity and apoptosis.Semantic proximity Read ↗

Genome-wide discovery of loci influencing chemotherapy cytotoxicitySemantic proximity Read ↗

Identification of genetic variants contributing to cisplatin-induced cytotoxicity by use of a genomewide approach.Semantic proximity Read ↗

A genome-wide approach to identify genetic variants that contribute to etoposide-induced cytotoxicity.Semantic proximity Read ↗

Identifying genetic variants that contribute to chemotherapy-induced cytotoxicity.Semantic proximity Read ↗

Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populationsSemantic proximity Read ↗

Apoptosis in Drug Response.Semantic proximity Read ↗

Genetic variants associated with carboplatin-induced cytotoxicity in cell lines derived from Africans.Semantic proximity Read ↗

Pharmacogenomic Characterization of US FDA-approved Cytotoxic DrugsSemantic proximity Read ↗

Genetic variants contributing to daunorubicin-induced cytotoxicity.Semantic proximity Read ↗

Mapping genes that contribute to daunorubicin-induced cytotoxicity.Semantic proximity Read ↗

Application of next generation sequencing to CEPH cell lines to discover variants associated with FDA approved chemotherapeutics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.