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Article

Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA.

Molecular microbiology - 1 Mar 2008

Soriani Frederico Marianetti, Malavazi Iran, da Silva Ferreira Márcia Eliana, Savoldi Marcela, Von Zeska Kress Marcia Regina, de Souza Goldman Maria Helena, Loss Omar, Bignell Elaine, Goldman Gustavo Henrique

Abstract excerpt

The protein phosphatase calcineurin is an important mediator connecting calcium-dependent signalling to various cellular responses in multiple organisms. In fungi calcineurin acts largely through regulating Crz1p-like transcription factors. Here we characterize an Aspergillus fumigatus CRZ1 homologue, CrzA and demonstrate its mediation of cellular tolerance to increased concentrations of calcium and manganese. In...

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PMID: 18298443
DOI: 10.1111/j.1365-2958.2008.06122.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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