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Article

Calcineurin Controls Hyphal Growth, Virulence, and Drug Tolerance of Candida tropicalis

18 Jan 2014

Abstract excerpt

Candida tropicalis, a species closely related to Candida albicans, is an emerging fungal pathogen associated with high mortality rates of 40 to 70%. Like C. albicans and Candida dubliniensis, C. tropicalis is able to form germ tubes, pseudohyphae, and hyphae, but the genes involved in hyphal growth machinery and virulence remain unclear in C. tropicalis. Recently, echinocandin- and azole-resistant C. tropicalis...

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PMID: 24442892
DOI: 10.1128/ec.00302-13

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