Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional Characterization of an Aspergillus fumigatus Calcium Transporter (PmcA) that Is Essential for Fungal Infection

23 May 2012

Abstract excerpt

Aspergillus fumigatus is a primary and opportunistic pathogen, as well as a major allergen, of mammals. The Ca(+2)-calcineurin pathway affects virulence, morphogenesis and antifungal drug action in A. fumigatus. Here, we investigated three components of the A. fumigatus Ca(+2)-calcineurin pathway, pmcA,-B, and -C, which encode calcium transporters. We demonstrated that CrzA can directly control the mRNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Peptidase Inhibition and Analysis
Share to Signaling Pathways in Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22649543
DOI: 10.1371/journal.pone.0037591

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional Characterization of an Aspergillus fumigatus Calcium Transporter (PmcA) that Is Essential for Fungal InfectionPMID 22649543Read ↗

Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA.Semantic proximity Read ↗

Functional characterization of the Aspergillus fumigatus calcineurin.Semantic proximity Read ↗

Identification of possible targets of the Aspergillus fumigatus CRZ1 homologue, CrzA.Semantic proximity Read ↗

Aspergillus fumigatus calcium-responsive transcription factors regulate cell wall architecture promoting stress tolerance, virulence and caspofungin resistance.Semantic proximity Read ↗

Updating Insights into the Regulatory Mechanisms of Calcineurin-Activated Transcription Factor Crz1 in Pathogenic FungiSemantic proximity Read ↗

Mitochondrial dysfunctions trigger the calcium signaling-dependent fungal multidrug resistanceSemantic proximity Read ↗

Calcineurin‐dependent dephosphorylation of the transcription factor CrzA at specific sites controls conidiation, stress tolerance, and virulence of Aspergillus fumigatusSemantic proximity Read ↗

Calcineurin Controls Hyphal Growth, Virulence, and Drug Tolerance of Candida tropicalisSemantic proximity Read ↗

The calcineurin pathway regulates extreme thermotolerance, cell membrane and wall integrity, antifungal resistance, and virulence in Candida aurisSemantic proximity Read ↗

CRZ1, a target of the calcineurin pathway in Candida albicans.Semantic proximity Read ↗

Elucidation of the calcineurin-Crz1 stress response transcriptional network in the human fungal pathogen Cryptococcus neoformans.Semantic proximity Read ↗

RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.