CRZ1, a target of the calcineurin pathway in Candida albicans.

doi:10.1111/j.1365-2958.2005.05037.x

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Article

CRZ1, a target of the calcineurin pathway in Candida albicans.

Molecular microbiology - 1 Mar 2006

Karababa Mahir, Valentino Emilio, Pardini Giacomo, Coste Alix T, Bille Jacques, Sanglard Dominique

Abstract excerpt

Calcineurin is a major player in calcium-dependent signal transduction pathways of eukaryotes. Calcineurin acts on transcription factors (e.g. CRZ1 in Saccharomyces cerevisiae) and governs the expression of genes in a species-dependent fashion. In Candida albicans, the calcineurin pathway is involved in tolerance to antifungal agents, cation homeostasis and virulence. However, the components of the calcineurin...

Topics

Animals
Antifungal Agents
Calcineurin
Calcium
Candida albicans
Candidiasis
Cell Nucleus
Female
Fungal Proteins
Gene Expression Regulation, Fungal
Genome, Fungal
Glycoside Hydrolases
Intracellular Signaling Peptides and Proteins
Mice

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Open in PubMed

Identifiers

PMID: 16468987
DOI: 10.1111/j.1365-2958.2005.05037.x

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred BALB C

Mutation

Regulatory Sequences, Nucleic Acid

Saccharomyces cerevisiae Proteins