Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CRZ1, a target of the calcineurin pathway in Candida albicans.

Molecular microbiology - 1 Mar 2006

Karababa Mahir, Valentino Emilio, Pardini Giacomo, Coste Alix T, Bille Jacques, Sanglard Dominique

Abstract excerpt

Calcineurin is a major player in calcium-dependent signal transduction pathways of eukaryotes. Calcineurin acts on transcription factors (e.g. CRZ1 in Saccharomyces cerevisiae) and governs the expression of genes in a species-dependent fashion. In Candida albicans, the calcineurin pathway is involved in tolerance to antifungal agents, cation homeostasis and virulence. However, the components of the calcineurin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal Agents
Share to Calcineurin
Share to Candida albicans

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Candidiasis

Share to Genome, Fungal

Share to Glycoside Hydrolases

Share to Regulatory Sequences, Nucleic Acid

Share to Zinc Fingers

Source

Identifiers

PMID: 16468987
DOI: 10.1111/j.1365-2958.2005.05037.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CRZ1, a target of the calcineurin pathway in Candida albicans.PMID 16468987Read ↗

Calcineurin acts through the CRZ1/TCN1-encoded transcription factor to regulate gene expression in yeast.Semantic proximity Read ↗

Identification of possible targets of the Aspergillus fumigatus CRZ1 homologue, CrzA.Semantic proximity Read ↗

Elucidation of the calcineurin-Crz1 stress response transcriptional network in the human fungal pathogen Cryptococcus neoformans.Semantic proximity Read ↗

RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans.Semantic proximity Read ↗

The Crz1/Sp1 Transcription Factor of Cryptococcus neoformans Is Activated by Calcineurin and Regulates Cell Wall IntegritySemantic proximity Read ↗

Regulation of salt tolerance by Torulaspora delbrueckii calcineurin target Crz1p.Semantic proximity Read ↗

Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA.Semantic proximity Read ↗

Elucidating the Candida albicans calcineurin signaling cascade controlling stress response and virulence.Semantic proximity Read ↗

Updating Insights into the Regulatory Mechanisms of Calcineurin-Activated Transcription Factor Crz1 in Pathogenic FungiSemantic proximity Read ↗

The Calcineurin Target, Crz1, Functions in Azole Tolerance but Is Not Required for Virulence of <i>Candida albicans</i>Semantic proximity Read ↗

Convergent Evolution of Calcineurin Pathway Roles in Thermotolerance and Virulence in<i>Candida glabrata</i>Semantic proximity Read ↗

Roles of calcineurin and Crz1 in antifungal susceptibility and virulence of Candida glabrata.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.