Article
Functional characterization of the Aspergillus fumigatus calcineurin.
Fungal genetics and biology : FG & B - 1 Mar 2007
da Silva Ferreira Márcia Eliana, Heinekamp Thorsten, Härtl Albert, Brakhage Axel A, Semighini Camile P, Harris Steven D, Savoldi Marcela, de Gouvêa Paula Fagundes, de Souza Goldman Maria Helena, Goldman Gustavo H
Abstract excerpt
Aspergillus fumigatus is an aggressive opportunistic pathogen of humans as well as a major allergen. Environmental sensing and retrieving essential nutrients from the environment are general metabolic traits associated with the growth of this saprophytic fungus. Two important mediators of calcium signals in eukaryotic cells are the Ca(2+)-binding protein calmodulin and the Ca(2+)/calmodulin-dependent phosphatase...
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