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Article

Roles of calcineurin and Crz1 in antifungal susceptibility and virulence of Candida glabrata.

Antimicrobial agents and chemotherapy - 1 Apr 2010

Miyazaki Taiga, Yamauchi Shunsuke, Inamine Tatsuo, Nagayoshi Yosuke, Saijo Tomomi, Izumikawa Koichi, Seki Masafumi, Kakeya Hiroshi, Yamamoto Yoshihiro, Yanagihara Katsunori, Miyazaki Yoshitsugu, Kohno Shigeru

Abstract excerpt

A Candida glabrata calcineurin mutant exhibited increased susceptibility to both azole antifungal and cell wall-damaging agents and was also attenuated in virulence. Although a mutant lacking the downstream transcription factor Crz1 displayed a cell wall-associated phenotype intermediate to that...

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Identifiers

PMID: 20100876
DOI: 10.1128/AAC.01364-09
PMCID: PMC2849377

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20100876-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Roles of calcineurin and Crz1 in antifungal susceptibility and virulence of Candida glabrata.PMID 20100876Read ↗

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Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA.Semantic proximity Read ↗

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