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Article

Frequent mutations of the CA simple sequence repeat in intron 1 of EGFR in mismatch repair-deficient colorectal cancers.

World journal of gastroenterology - 21 Feb 2008

Buisine Marie-Pierre, Wacrenier Agnes, Mariette Christophe, Leteurtre Emmanuelle, Escande Fabienne, Aissi Sana, Ketele Amandine, Leclercq Annette, Porchet Nicole, Lesuffleur Thecla

Abstract excerpt

AIM: To investigate the polymorphic simple sequence repeat in intron 1 of the epidermal growth factor receptor gene (EGFR) (CA-SSR I), which is known to affect the efficiency of gene transcription as a putative target of the mismatch repair (MMR) machinery in colorectal tumors. METHODS: The CA-SSR I genotype was analyzed in a total of 86 primary colorectal tumors, selected upon their microsatellite instability...

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Share to Colorectal Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18286687
DOI: 10.3748/wjg.14.1053
PMCID: PMC2689408

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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