Article

Short tandem repeat mutations regulate gene expression in colorectal cancer

2023-11-29

Abstract excerpt

<h4>ABSTRACT</h4> Short tandem repeat (STR) mutations are prevalent in colorectal cancer (CRC), especially in tumours with the microsatellite instability (MSI) phenotype. While STR length variations are known to regulate gene expression under physiological conditions, the functional impact of STR mutations in CRC remains unclear. Here, we integrate STR mutation data with clinical information and gene expression l...

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Literature Corpus work: 18a0a9a8-f2bc-5fe3-adda-6e5f2c0740be
DOI: 10.1101/2023.11.29.569189

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