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Article

Distinct amplification of an untranslated regulatory sequence in the egfr gene contributes to early steps in breast cancer development.

Cancer research - 15 Mar 2003

Tidow Nicola, Boecker Almuth, Schmidt Hartmut, Agelopoulos Konstantin, Boecker Werner, Buerger Horst, Brandt Burkhard

Abstract excerpt

Overexpression of the epidermal growth factor receptor (egfr) gene is a common feature in breast cancer. We demonstrated recently that the expression of EGFR in breast cancer strongly correlates with the length of a CA simple sequence repeat within the first 2000 bases in intron 1 of the egfr gene [CA simple sequence repeat (CA-SSR) I; H. Buerger et al., Cancer Res., 60: 854-857, 2000]. Using a standardized...

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PMID: 12649171

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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