Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modification of Breast Cancer Risk in Young Women by a Polymorphic Sequence in the egfr Gene

1 Jan 2004

Abstract excerpt

The regulation of the epidermal growth factor receptor (egfr) gene in human cancer is not yet fully understood. Recent data on a polymorphic CA repeat located at the 5'-regulatory sequence in intron 1 of the egfr gene [egfr CA simple sequence repeat (SSR) I] point to a possible inheritance of cancer risk associated with the egfr gene. Furthermore, we have detected frequent allelic imbalances restricted to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA gene mutations in cancer
Share to Cancer-related Molecular Pathways
Share to Estrogen and related hormone effects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 14729599
DOI: 10.1158/0008-5472.can-03-2623

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modification of Breast Cancer Risk in Young Women by a Polymorphic Sequence in the egfr GenePMID 14729599Read ↗

Distinct amplification of an untranslated regulatory sequence in the egfr gene contributes to early steps in breast cancer development.Semantic proximity Read ↗

Allelic length of a CA dinucleotide repeat in the egfr gene correlates with the frequency of amplifications of this sequence--first results of an inter-ethnic breast cancer study.Semantic proximity Read ↗

Biological importance of a polymorphic CA sequence within intron 1 of the epidermal growth factor receptor gene (EGFR) in high grade central osteosarcomas.Semantic proximity Read ↗

Modulation of EGFR gene transcription by secondary structures, a polymorphic repetitive sequence and mutations--a link between genetics and epigenetics.Semantic proximity Read ↗

Lack of evidence for prognostic value of epidermal growth factor receptor intron-1 CA repeats for oral carcinomas.Semantic proximity Read ↗

Mechanisms of<i>egfr</i>Gene Transcription Modulation: Relationship to Cancer Risk and Therapy ResponseSemantic proximity Read ↗

Length and loss of heterozygosity of an intron 1 polymorphic sequence of egfr is related to cytogenetic alterations and epithelial growth factor receptor expression.Semantic proximity Read ↗

EGFR Intron 1 polymorphism in Asian Populations and its correlation with EGFR gene expression and amplification in breast tumor tissues.Semantic proximity Read ↗

An epidermal growth factor receptor intron 1 polymorphism mediates response to epidermal growth factor receptor inhibitors.Semantic proximity Read ↗

Association of the EGFR intron 1 CA repeat length with lung cancer risk.Semantic proximity Read ↗

Polymorphisms, mutations, and amplification of the EGFR gene in non-small cell lung cancers.Semantic proximity Read ↗

Association between the length of a CA dinucleotide repeat in the EGFR and risk of breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.