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Article

Factors associated with paraoxonase genotypes and activity in a diverse, young, healthy population: the Coronary Artery Risk Development in Young Adults (CARDIA) study.

Clinical chemistry - 1 Apr 2008

Thyagarajan Bharat, Jacobs David R, Carr J Jeffery, Alozie Ogechika, Steffes Michael W, Kailash Poonguzhali, Hayes Jennifer H, Gross Myron D

Abstract excerpt

BACKGROUND: Paraoxonase may mitigate oxidative damage and thus lower risk of macrovascular disease. METHODS: DNA samples from 2252 participants in the Coronary Artery Risk Development in Young Adults (CARDIA) study were genotyped for the L55M and Q192R polymorphisms of the PON1 (paraoxonase 1) gene, and paraoxonase activity was measured in serum. RESULTS: The 192R (67.4% vs 29.7%) and 55L (80.0% vs 63.8%) alleles...

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Source

Identifiers

PMID: 18281420
DOI: 10.1373/clinchem.2007.099044

Genes

PON1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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