Article
Paraoxonase 1 gene polymorphisms and enzyme activities in coronary artery disease and its relationship to serum lipids and glycemia.
Archivos de cardiologia de Mexico - 1 Jan 2000
Fridman Osvaldo, Gariglio Luis, Riviere Stephanie, Porcile Rafael, Fuchs Alicia, Potenzoni Miguel
Abstract excerpt
OBJECTIVES: Oxidative stress and inflammation are important processes in development of atherosclerosis. Paraoxonase 1 (PON1) is a bioscavenger enzyme associated with inflammation and oxidative stress. We evaluate the association of two single nucleotide polymorphisms in PON1 gene, and enzyme activities with lipid profile and glycemia. METHODS: This case-control study consisted of 126 patients with coronary...
Topics
- Aryldialkylphosphatase
- Blood Glucose
- Case-Control Studies
- Cholesterol
- Coronary Artery Disease
- Female
- Humans
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
- Triglycerides