Article
Association of PON1 gene polymorphisms and enzymatic activity with risk of coronary artery disease.
Future cardiology - 1 Jan 2021
Godbole Charuta, Thaker Saket, Kerkar Prafulla, Nadkar Milind, Gogtay Nithya, Thatte Urmila
Abstract excerpt
Background: The present case-control study evaluated the association of PON1 gene polymorphisms and enzyme activity in the western Indian population. Materials & methods: Angiographically proven coronary artery disease (CAD) formed the cases. PON1 polymorphisms (Q192R, L55M) and enzymatic activity (paraoxonase) were assessed. Results: A total of 502 participants (251 per group) were studied. PON1 Q192R and L55M...
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