Article
Paraoxonase 1 polymorphisms and risk of myocardial infarction in women and men.
Circulation journal : official journal of the Japanese Circulation Society - 1 Jul 2009
Mukamal Kenneth J, Pai Jennifer K, Jensen Majken K, Rimm Eric B
Abstract excerpt
BACKGROUND: Previous studies of genetic variants of paraoxonase 1 (PON1) and coronary heart disease (CHD) have been conflicting and the modifying effects of lifestyle factors that affect PON1 activity are uncertain. METHODS AND RESULTS: In parallel nested case-control studies, the prospective associations between PON1 polymorphisms Q192R and L55M and incident CHD were examined among participants in the Nurses'...
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