Article
Determinants of paraoxonase activity in healthy adults.
Molecular nutrition & food research - 1 Dec 2010
Boesch-Saadatmandi Christine, Rimbach Gerald, Schrader Charlotte, Kofler Bettina M, Armah Christopher K, Minihane Anne M
Abstract excerpt
SCOPE: Paraoxonase-1 (PON-1), associated with HDL, is regarded as anti-atherogenic, attributed to its ability to hydrolyze oxidized lipids. Here, the impact of PON and apolipoprotein E genotypes, age, alcohol and HDL-cholesterol (HDL-C) on PON activity is examined. METHODS AND RESULTS: In total, 104 healthy UK adults participated in the study, with basal (PONA) and stimulated (PONB) PON-1 activities and...
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