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Article

Paraoxonase (PON)-1: a brief overview on genetics, structure, polymorphisms and clinical relevance.

Vascular health and risk management - 1 Jan 2018

Shunmoogam Nelusha, Naidoo Poobalan, Chilton Robert

Abstract excerpt

Paraoxonase-1 (PON1) is a high-density lipoprotein-associated esterase and is speculated to play a role in several human diseases including diabetes mellitus and atherosclerosis. Low PON1 activity has been associated with increased risk of major cardiovascular events, therefore a variety of studies have been conducted to establish the cardioprotective properties and clinical relevance of PON1. The major aim of...

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Identifiers

PMID: 29950852
DOI: 10.2147/VHRM.S165173
PMCID: PMC6014389

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Paraoxonase (PON)-1: a brief overview on genetics, structure, polymorphisms and clinical relevance.PMID 29950852Read ↗

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