Article
Paraoxonase-1 and oxidized lipoprotein lipids. The Cardiovascular Risk in Young Finns Study.
Atherosclerosis - 1 Aug 2015
Kresanov Petri, Vasankari Tommi, Ahotupa Markku, Kaikkonen Jari, Hutri-Kähönen Nina, Juonala Markus, Kähönen Mika, Lehtimäki Terho, Viikari Jorma, Raitakari Olli T
Abstract excerpt
OBJECTIVE: Paraoxonase-1 (PON1) is suggested to have a role in the antioxidant activity of high-density lipoprotein (HDL). PON1 activity levels are strongly genetically determined by the rs662 polymorphism (PON1 Q192R). To clarify the role of PON1 in lipoprotein oxidation at the population level, we examined the relations between PON1 activity, the rs662 polymorphism and oxidized lipoprotein lipids in young...
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