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Article

SNP haplotype tagging from DNA pools of two individuals.

BMC bioinformatics - 22 Apr 2003

Hoh Josephine, Matsuda Fumihiko, Peng Xu, Markovic Daniela, Lathrop Mark G, Ott Jurg

Abstract excerpt

BACKGROUND: DNA pooling is a technique to reduce genotyping effort while incurring only minor losses in accuracy of allele frequency estimates for single nucleotide polymorphism (SNP) markers. RESULTS: We present an algorithm for reconstructing haplotypes (alleles for multiple SNPs on same chromosome) from pools of two individual DNAs, in which Hardy-Weinberg equilibrium conditions or other assumptions are not...

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Identifiers

PMID: 12709267
DOI: 10.1186/1471-2105-4-14
PMCID: PMC156884

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Source receipt: pubmed, retrieved 7 Sept 2026.

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