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Article

CD4+ target cell availability determines the dynamics of immune escape and reversion in vivo.

Journal of virology - 1 Apr 2008

Petravic Janka, Loh Liyen, Kent Stephen J, Davenport Miles P

Abstract excerpt

Infections with human immunodeficiency virus (HIV) and the closely related monkey viruses simian-human immunodeficiency virus (SHIV) and simian immunodeficiency virus (SIV) are characterized by progressive waves of immune responses, followed by viral mutation and "immune escape." However, escape mutation usually leads to lower replicative fitness, and in the absence of immune pressure, an escape mutant (EM) virus...

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Identifiers

PMID: 18272587
DOI: 10.1128/JVI.02552-07
PMCID: PMC2293002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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