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Article

Dynamics of immune escape during HIV/SIV infection.

PLoS computational biology - 18 Jul 2008

Althaus Christian L, De Boer Rob J

Abstract excerpt

Several studies have shown that cytotoxic T lymphocytes (CTLs) play an important role in controlling HIV/SIV infection. Notably, the observation of escape mutants suggests a selective pressure induced by the CTL response. However, it remains difficult to assess the definite role of the cellular immune response. We devise a computational model of HIV/SIV infection having a broad cellular immune response targeting...

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Share to Simian Immunodeficiency Virus
Share to Cytotoxicity, Immunologic
Share to Epitopes, T-Lymphocyte

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Simian Acquired Immunodeficiency Syndrome

Source

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Identifiers

PMID: 18636096
DOI: 10.1371/journal.pcbi.1000103
PMCID: PMC2423483

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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