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Article

Modelling the spread of HIV immune escape mutants in a vaccinated population.

PLoS computational biology - 1 Dec 2011

Fryer Helen R, McLean Angela R

Abstract excerpt

Because cytotoxic T-lymphocytes (CTLs) have been shown to play a role in controlling human immunodeficiency virus (HIV) infection and because CTL-based simian immunodeficiency virus (SIV) vaccines have proved effective in non-human primates, one goal of HIV vaccine design is to elicit effective CTL responses in humans. Such a vaccine could improve viral control in patients who later become infected, thereby...

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Identifiers

PMID: 22144883
DOI: 10.1371/journal.pcbi.1002289
PMCID: PMC3228780

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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