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Article

A protective role of mast cells in intestinal tumorigenesis

6 Feb 2008

Abstract excerpt

Mast cells have been observed in numerous types of tumors; however, their role in carcinogenesis remains poorly understood. The majority of epidemiological evidence suggests a negative association between the presence of mast cells and tumor progression in breast, lung and colonic neoplasms. Intestinal adenomas in the multiple intestinal neoplasia (Min, APC(Min/+)) mouse displayed increased numbers of mast cells...

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PMID: 18258601
DOI: 10.1093/carcin/bgn040

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