Article
Loss of functional Fas ligand enhances intestinal tumorigenesis in the Min mouse model.
Cancer research - 15 May 2007
Fingleton Barbara, Carter Kathy J, Matrisian Lynn M
Abstract excerpt
Fas ligand (FasL/CD95L), a member of the tumor necrosis factor family, interacts with a specific receptor Fas, ultimately leading to cell death. Tumor expression of FasL has been proposed to aid in immune evasion through a "Fas counterattack" mechanism but has also been described as a proinflamma...
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