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Article

MEN1 and FANCD2 mediate distinct mechanisms of DNA crosslink repair.

DNA repair - 1 Mar 2008

Marek Lorri R, Kottemann Molly C, Glazer Peter M, Bale Allen E

Abstract excerpt

Cells mutant for multiple endocrine neoplasia type I (MEN1) or any of the Fanconi anemia (FA) genes are hypersensitive to the killing effects of crosslinking agents, but the precise roles of these genes in the response to interstrand crosslinks (ICLs) are unknown. To determine if MEN1 and the FA genes function cooperatively in the same repair process or in distinct repair processes, we exploited Drosophila...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18258493
DOI: 10.1016/j.dnarep.2007.12.009
PMCID: PMC2277339

Genes

MEN1
FANCD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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