Article
Arabidopsis thaliana FANCONI ANAEMIA I (FANCI) has roles in the repair of interstrand crosslinks and CRISPR-Cas9 induced DNA double strand breaks.
The Plant journal : for cell and molecular biology - 1 Oct 2025
Balobaid Atheer, Waterworth Wanda M, Vila Nova Sophya F, Causier Barry, Sharma Vinay, Park Madeline R, Pandey Manish K, West Christopher E
Abstract excerpt
DNA repair is crucial for genome stability, in particular for plants which are exposed to high levels of damage arising from UV irradiation, soil pollutants and reactive oxygen species. Damage that affects both strands of the DNA duplex is harder to repair due to both the lack of a template strand and the potential for physical separation of fragmented chromosomes. As such, DNA double-strand breaks (DSBs) and...
Read the complete abstract on PubMedTopics
- Arabidopsis
- Arabidopsis Proteins
- DNA Repair
- DNA Breaks, Double-Stranded
- CRISPR-Cas Systems