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Article

Drosophila homologs of FANCD2 and FANCL function in DNA repair.

DNA repair - 8 Nov 2006

Marek Lorri R, Bale Allen E

Abstract excerpt

Fanconi anemia (FA) is a genetically heterogeneous disease characterized by developmental defects, progressive bone marrow failure and cancer susceptibility. Cells derived from patients with FA show spontaneous chromosomal aberrations and hypersensitivity to cross-linking agents, indicating a cellular defect in DNA repair. Among the 12 FA genes, only FANCD2, FANCL and FANCM have Drosophila homologs. Given this...

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Source

Identifiers

PMID: 16860002
DOI: 10.1016/j.dnarep.2006.05.044

Genes

FANCD2
FANCL
FANCM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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