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Article

The phenotype of FancB-mutant mouse embryonic stem cells.

Mutation research - 1 Jul 2011

Kim Tae Moon, Ko Jun Ho, Choi Yong Jun, Hu Lingchuan, Hasty Paul

Abstract excerpt

Fanconi anemia (FA) is a rare autosomal recessive disease characterized by bone marrow failure, developmental defects and cancer. There are multiple FA genes that enable the repair of interstrand crosslinks (ICLs) in coordination with a variety of other DNA repair pathways in a way that is poorly understood. Here we present the phenotype of mouse embryonic stem (ES) cells mutated for FancB. We found FancB-mutant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21458466
DOI: 10.1016/j.mrfmmm.2011.03.010
PMCID: PMC3109163

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