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Article

Expression of a GRM3 splice variant is increased in the dorsolateral prefrontal cortex of individuals carrying a schizophrenia risk SNP.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Oct 2008

Sartorius Leah J, Weinberger Daniel R, Hyde Thomas M, Harrison Paul J, Kleinman Joel E, Lipska Barbara K

Abstract excerpt

Genetic variation in the metabotropic glutamate receptor 3 (GRM3, mGluR3) has been associated with schizophrenia, but the mechanism by which it confers risk is unknown. Previously, we reported the existence of a splice variant, GRM3Delta4, which has an exon 4 deletion and encodes a truncated form of the receptor that is expressed in brain. The aim of the present study was to determine whether expression of this...

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Source

Identifiers

PMID: 18256595
DOI: 10.1038/sj.npp.1301669

Genes

GRM3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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